PhD Program in Montepllier

 

---

De : Didier MARGUET
Envoyé : vendredi 13 mars 2009 13:59
À : labs
Objet : TR: PhD Program in Montepllier

 

 

An International PhD Program was recently created by the Doctoral School «CBS2-Sciences Chimiques et Biologiques pour la Santé » to attract students who wish to undertake a thesis financed by french government. In 2009, 18 PhD grants will be attributed. General information about Program statutes, students selection, associated research groups and online application form are available on the website : http://ecole-doctorale-cbs2.igh.cnrs.fr/

Warning : the deadline for online application to the Program is march, 30th 2009

Quantitative analysis of catabolic regulation in single bacterial live cells and complex solutions using fluorescence fluctuation spectroscopy and imaging

Contact for this proposal: Dr. Nathalie Declerck or Cathy Royer, Centre de Biochimie Structurale, CNRS-INSERM, 29 rue de Navacelles, 34090 Montpellier France
nathalie@cbs.cnrs.fr, royer@cbs.cnrs.fr
 
This thesis project aims at the quantitative characterization of a model biological system, the regulation of the central carbon metabolism (CCM) in Gram positive bacteria using state-of-the-art biophotonics methodologies on single molecules based primarily on fluorescence fluctuation spectroscopy (FFS), both in vivo and in vitro. The results obtained in single live cells will be compared with those obtained in solution and crowded media, providing insights into the missing link between in vitro characterization of transcription factors and their functioning in the cellular environment. These results will be interpreted in the context of structure-function and systems biology studies within a long-term collaborative project between the Centre de Biochimie Structurale (CBS in Montpellier) and the Laboratoire de Microbiologie et Génétique Moléculaire (at INRA AgroParisTech). 
The student will use two-photon two-colour fluorescence fluctuation methods on the setup now available at the CBS. With this instrument, fluorescent correlation and cross-correlation spectroscopy (FCS and FCCS) measurements have already been performed for in vitro characterization of different interacting macromolecules, as well as live-cell quantification of the conditional interaction of human nuclear receptors with co-regulators. In addition to classical fluctuation measurement, we will implement other innovative fluorescence fluctuation spectroscopy and imaging techniques, in particular scanning FCS (sFCS), Raster Scanning Image Correlation Spectroscopy (RICS), Number and Brightness Analysis (NBA) and PhotoActivatible Localization Microscopy (PALM).
In the context of these studies the PhD student will study in particular, the interactions between diffusing transcription factors implicated in CCM regulation in Bacillus subtilis using two color, two photon fluorescence cross-correlation spectroscopy in live cells. The dynamics and stochastic nature of the cellular response will be investigated in single bacterial cells under different growth conditions and carbon sources. Preliminary data on GFP reporter expression from CCM promoters in B. subtilis using two photon FCS has already demonstrate the feasibility of such studies in vivo. Encouraging results have also already been obtained in vitro in complex solutions suggesting that molecular crowding significantly modifies the interactions of transcription factors with DNA and effector ligands. Thus, this thesis project is based on very strong preliminary results.

Nathalie DECLERCK

Centre de Biochimie Structurale
INSERM U554/CNRS 5048
29 rue de Navacelles
F-34090 Montpellier, France
Tel: 33 4 67 41 79 11
Fax: 33 4 67 41 79 13
e-mail: nathalie@cbs.cnrs.fr

PhD Program in Montepllier
>
>
>An International PhD Program was recently created by the Doctoral School
>«CBS2-Sciences Chimiques et Biologiques pour la Santé » to attract
>students who wish to undertake a thesis financed by french government. In
>2009, 18 PhD grants will be attributed. General information about Program
>statutes, students selection, associated research groups and online
>application form are available on the website :
>http://ecole-doctorale-cbs2.igh.cnrs.fr/
>
>Warning : the deadline for online application to the Program is march,
>30th 2009
>
>Quantitative analysis of catabolic regulation in single bacterial live
>cells and complex solutions using fluorescence fluctuation spectroscopy
>and imaging
>
>Contact for this proposal: Dr. Nathalie Declerck or Cathy Royer, Centre de
>Biochimie Structurale, CNRS-INSERM, 29 rue de Navacelles, 34090
>Montpellier France
>nathalie@cbs.cnrs.fr, royer@cbs.cnrs.fr
>
>This thesis project aims at the quantitative characterization of a model
>biological system, the regulation of the central carbon metabolism (CCM)
>in Gram positive bacteria using state-of-the-art biophotonics
>methodologies on single molecules based primarily on fluorescence
>fluctuation spectroscopy (FFS), both in vivo and in vitro. The results
>obtained in single live cells will be compared with those obtained in
>solution and crowded media, providing insights into the missing link
>between in vitro characterization of transcription factors and their
>functioning in the cellular environment. These results will be interpreted
>in the context of structure-function and systems biology studies within a
>long-term collaborative project between the Centre de Biochimie
>Structurale (CBS in Montpellier) and the Laboratoire de Microbiologie et
>Génétique Moléculaire (at INRA AgroParisTech).
>The student will use two-photon two-colour fluorescence fluctuation
>methods on the setup now available at the CBS. With this instrument,
>fluorescent correlation and cross-correlation spectroscopy (FCS and FCCS)
>measurements have already been performed for in vitro characterization of
>different interacting macromolecules, as well as live-cell quantification
>of the conditional interaction of human nuclear receptors with
>co-regulators. In addition to classical fluctuation measurement, we will
>implement other innovative fluorescence fluctuation spectroscopy and
>imaging techniques, in particular scanning FCS (sFCS), Raster Scanning
>Image Correlation Spectroscopy (RICS), Number and Brightness Analysis
>(NBA) and PhotoActivatible Localization Microscopy (PALM).
>In the context of these studies the PhD student will study in particular,
>the interactions between diffusing transcription factors implicated in CCM
>regulation in Bacillus subtilis using two color, two photon fluorescence
>cross-correlation spectroscopy in live cells. The dynamics and stochastic
>nature of the cellular response will be investigated in single bacterial
>cells under different growth conditions and carbon sources. Preliminary
>data on GFP reporter expression from CCM promoters in B. subtilis using
>two photon FCS has already demonstrate the feasibility of such studies in
>vivo. Encouraging results have also already been obtained in vitro in
>complex solutions suggesting that molecular crowding significantly
>modifies the interactions of transcription factors with DNA and effector
>ligands. Thus, this thesis project is based on very strong preliminary
>results.
>
>
>
>
>
>Nathalie DECLERCK
>
>Centre de Biochimie Structurale
>INSERM U554/CNRS 5048
>29 rue de Navacelles
>F-34090 Montpellier, France
>Tel: 33 4 67 41 79 11
>Fax: 33 4 67 41 79 13
>e-mail: nathalie@cbs.cnrs.fr
>
>
>_______________________________________________
>Research mailing list
>Research@igc.gulbenkian.pt
>https://lists.igc.gulbenkian.pt/mailman/listinfo/research

BOLSAS DE ESTUDO NO ESTRANGEIRO DE CURTA DURAÇÃO E SUBSÍDIOS PARA PARTICIPAÇÃO EM CONGRESSOS INTERNACIONAIS FUNDAÇÃO CALOUSTE GULBENKIAN

PRAZO   1 DE ABRIL DE 2009: Para deslocações a começar entre 16 de Abril e 15 de Junho de 2009.
Próximos concursos: 01/06/2009 (deslocações entre 16-08 e 31-10-2009); 15/08/2009 (deslocações entre 01-11-2009 e 31-01-2010); 15-11-2009 (deslocações entre 01-02-2010 e 15-04-2010).

Tipologia       Bolsas de Estudo no Estrangeiro de Curta Duração
Estas bolsas visam a realização de estudos de pós-graduação no estrangeiro, com a duração de 16 dias e 3 meses, com o objectivo de fomentar a aprendizagem, a recolha e consulta bibliográfica, a discussão e redacção de teses de doutoramento ou artigos científicos.
Estas bolsas destinam-se apenas a licenciados, mestres, doutorados ou doutorandos (não estando abrangidos mestrandos).
As candidaturas deverão ser apresentadas através de formulário electrónico disponível no edital do Concurso: http://www.gulbenkian.pt/index.php?section=65&artId=412

Subsídios para a Participação em Congressos Internacionais
Poderão concorrer a estes subsídios Licenciados, Mestres e Doutorados para apresentação de comunicações em congressos e/ou outras reuniões científicas internacionais e, ainda, para estágios curtos, até 15 dias, em centros de investigação no estrangeiro.
As candidaturas deverão ser apresentadas através de formulário electrónico disponível no edital do Concurso: http://www.gulbenkian.pt/index.php?section=65&artId=940

Anúncio http://www.gulbenkian.pt/index.php?section=65&artId=454

Organismo       Fundação Calouste Gulbenkian
Contactos       Email: bolsas@gulbenkian.pt


GAP - Gabinete de Apoio a Projectos


10 de Março de 2009

Postdoctoral position available

Dear Colleagues,

I have a postdoctoral position available in my laboratory for someone interested in acquiring undergraduate teaching and research mentoring experience while doing research in the area of Tetrahymena chromatin biology. My lab is in the Joint Science Department of the Claremont Colleges in Southern California, and the position is available starting April, 2009. I would appreciate your help by forwarding this on to any graduate student of postdoc you know who may be interested.  It is ideal for anyone considering a career integrating teaching and research. The full job description is copied below.

Thank you,

Emily

TEACHING POSTDOCTORAL POSITION

 

Title:  Teaching Postdoctoral Fellow

 

Where: Joint Science Department of the Claremont Colleges, Claremont, CA

 

Subject Areas: Molecular biology, chromatin biology

 

Duration: 2 years, negotiable

 

Start date: April, 2009; negotiable

 

Description:  The successful candidate will carry out research related to the identification an d characterization of proteins involved in chromatin structure dynamics using the ciliate model Tetrahymena thermophila.  Other responsibilities include mentoring undergraduate research projects and developing/teaching courses in the general areas of molecular/cell biology, genetics, or biochemistry. Courses in other areas would also be possible. The teaching load is negotiable, but can vary between one half course and two courses per year depending on interest. Leadership in a collaborative undergraduate research initiative is also possible.

 

The Claremont Colleges are a consortium of adjacent highly selective undergraduate liberal arts colleges. The campuses, which include Scripps, Claremont McKenna, Pitzer, Harvey-Mudd, and Pomona Colleges, are located east of Los Angeles in the foothills of the San Gabriel Mountains, close to Cal-Tech and a short dri ve from other state universities including UCLA, USC, and UC Irvine.

 

The Joint Science Department of the Scripps, Claremont McKenna, and Pitzer Colleges is an interdisciplinary department of 30+ faculty representing Chemistry, Biology, and Physics. The department is housed in a modern well-equipped facility, and has external funding from NSF, NIH, and a number of private foundations. See the W.M. Keck Joint Science Center website (http://www.jsd.claremont.edu/).

 

For more information contact:              Dr. Emily Wiley 

                                                               ewiley@jsd.claremont.edu

 

           

To Apply:  Send a CV, a list of 3-4 references with contact information, and a cover letter summarizing research experience and any previous teaching experience and/or motivation toward a college teaching/research career. Review of applications will begin immediately.

 

 

Email mat erials to:             Emily Wiley

                                    ewiley@jsd.claremont.edu

                                   

>TEACHING POSTDOCTORAL POSITION
>
>
>Title:  Teaching Postdoctoral Fellow
>
>Where: Joint Science Department of the Claremont Colleges, Claremont, CA
>
>Subject Areas: Molecular biology, chromatin biology
>
>Duration: 2 years, negotiable
>
>Start date: April, 2009; negotiable
>
>Description:  The successful candidate will carry out research
>related to the identification and characterization of proteins
>involved in chromatin structure dynamics using the ciliate model
>Tetrahymena thermophila.  Other responsibilities include mentoring
>undergraduate research projects and developing/teaching courses in
>the general areas of molecular/cell biology, genetics, or
>biochemistry. Courses in other areas would also be possible. The
>teaching load is negotiable, but can vary between one half course and
>two courses per year depending on interest. Leadership in a
>collaborative undergraduate research initiative is also possible.
>
>The Claremont Colleges are a consortium of adjacent highly selective
>undergraduate liberal arts colleges. The campuses, which include
>Scripps, Claremont McKenna, Pitzer, Harvey-Mudd, and Pomona Colleges,
>are located east of Los Angeles in the foothills of the San Gabriel
>Mountains, close to Cal-Tech and a short drive from other state
>universities including UCLA, USC, and UC Irvine.
>
>The Joint Science Department of the Scripps, Claremont McKenna, and
>Pitzer Colleges is an interdisciplinary department of 30+ faculty
>representing Chemistry, Biology, and Physics. The department is
>housed in a modern well-equipped facility, and has external funding
>from NSF, NIH, and a number of private foundations. See the W.M. Keck
>Joint Science Center website (http://www.jsd.claremont.edu/).
>
>
>For more information contact:              Dr. Emily Wiley
>
>ewiley@jsd.claremont.edu
>
>
>To Apply:  Send a CV, a list of 3-4 references with contact
>information, and a cover letter summarizing research experience and
>any previous teaching experience and/or motivation toward a college
>teaching/research career. Review of applications will begin immediately.
>
>
>Email materials to:             Emily Wiley
>                                      ewiley@jsd.claremont.edu
>
>
>

Concurso para Atribuição de Bolsa de Investigação Científica

Concurso para Atribuição de Bolsa de Investigação Científica
Encontra-se aberto um concurso para atribuição de uma Bolsa de Investigação Científica (BI) com as
seguintes condições:
1. Duração e Regime de Actividade – Duração de 6 meses, com entrada imediata, em regime de
exclusividade, conforme regulamento de formação avançada de Recursos Humanos da Fundação para a
Ciência e Tecnologia (FCT).
2. Local de Trabalho – Decorrerá nas instalações do Departamento de Engenharia Civil, Universidade do
Minho, Campus de Azurém em Guimarães.
3. Objectivos de Actividade e Orientação Científica – O bolseiro será integrado numa equipa de trabalho
sob a orientação do Prof. José Barroso de Aguiar.
O objectivo principal do trabalho consiste em tomar conhecimento do desenvolvimento de um “tijolo ou bloco”
inovador em poliestireno expandido e interpretar os processos e os conceitos construtivos resultantes, para
desenvolver um estudo das especificações técnicas aplicáveis às alvenarias de blocos leves, de forma a que
se possa adequar e enquadrar este novo desenvolvimento de alvenarias às especificações e normas
Europeias, nomeadamente, European Organisation for Technical Approvals – EOTA.
O bolseiro receberá documentação do LNEC e executará um plano de trabalhos de acordo com as
especificações necessárias para a aprovação ou homologação deste produto nesta instituição, que inclui
essencialmente a análise das especificações técnicas aplicáveis, pormenores construtivos e avaliação
experimental.
4. Formação Académica – Os candidatos à Bolsa de Investigação Científica (BI) deverão preferencialmente
satisfazer os seguintes requisitos:

Licenciatura em Engenharia Civil;

Experiência de I&D ou industrial em assunto relevante ao projecto;

Bons conhecimentos da língua inglesa.
5. Critérios de Avaliação: Será valorizado o mérito do candidato, tendo em consideração os parâmetros da
formação académica, perfil curricular e experiência em investigação científica avaliados por possível
entrevista.
6. Remuneração – Remuneração de acordo com a tabela de valores das Bolsas de Investigação no País
atribuídas pela FCT – Fundação para a Ciência e a Tecnologia.
7. Condições – As candidaturas deverão ser acompanhadas de Curriculum Vitae e cópia do Certificado de
Habilitações.
8. Prazo e Recepção de Candidaturas – Todas as candidaturas deverão ser entregues em mão ou
enviadas pelo correio, entre os dias 9 e 20 de Março de 2009, no seguinte endereço:
TecMinho – Associação Universidade-Empresa para o Desenvolvimento
A/c Dra. Paula Dias
Candidatura a Bolsa de Investigação Científica
Universidade do Minho
Campus de Azurém
4800-058 Guimarães
Guimarães, 9 de Março de 2009

Ciclo de Conferências "A Evolução de Darwin" - Fundação Calouste Gulbenkian - 11 de Março - Auditório 2 - 18h00 - Tradução simultânea

O Serviço de Ciência da Fundação Calouste Gulbenkian, realiza no Auditório 2 da Fundação Calouste Gulbenkian  (Av. de Berna, 45 A)  a conferência  - GLAD TO HAVE EVOLVED -  que terá lugar no dia 11 de Março, às 18h00, e será proferida pela Profª OLIVIA JUDSON do Imperial College, Uk.   Teria muito gosto em que estivesse presente nesta iniciativa.



Poderá também assistir em directo através do site: http://live.fccn.pt/fcg/ <http://live.fccn.pt/fcg/>   e enviar as suas questões (darwin@gulbenkian.pt <mailto:darwin@gulbenkian.pt> ).

FW: PhD grants available, University of Minho, Portugal

The Department of Civil Engineering at University of Minho / Portugal wants to hire two PhD students, in the framework of externally funded R&D contracts. The work will be developed in the framework of structural engineering, namely with respect to innovative solutions for masonry structures, durability and reliability of structures, structural health monitoring or improved and innovative techniques for structural diagnosis.



We are looking for motivated individuals with sound knowledge of mechanics of materials and structures, able to develop individual work, capable of innovation, and strongly attracted to the field. Very good knowledge of English is an important requirement. Additional information about the Masonry Group at University of Minho can be found at www.civil.uminho.pt/masonry.



Applicants should send until March 31, 2009 a copy of their Curriculum Vitae together with a copy of their graduate certificate to Professor Paulo B. Lourenço, University of Minho, Portugal, e-mail: pbl@civil.uminho.pt.